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Papers On Chemistry
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Methadone and Metabolites -Description of analyte and its’ function
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This 8 page paper looks at the detection of methadone and it metabolites (by products). The paper begins with a description of the chemical structure of the methadone molecule and the identification of primary and secondary metabolites and their presence within the body. The paper then considers the different testing methodologies including immunoassay assay tests, thin layer chromatography, enzymatic analysis and gas chromatography-mass spectrometry. The bibliography cites 6 sources.
Filename: TEmethadone.rtf

Milk Proteins
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This 5 page paper outlines the properties of milk proteins. Whole milk contains a number of different proteins, including casein and caseinates, beta-lactoglobulin and alpha-lactalbumin, all of which are present in unprocessed milk and most commercial milk products. Bibliography lists 6 sources.
Filename: mhmilkpr.rtf

Molecular Mixtures and Cross-Membrane Transport
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A 5 page review of “Drug Delivery: Breaching the Membrane”, an article by Joe Alper published in the May 3, 2002 edition of “Science”. Alper’s (2002) research concentrates on the cell membrane and the manner in which cross-membrane transport occurs, specifically the manner in which membrane-bound protein transporters function to allow various nutrients and hormones across. Alper’s paper adds insight to both the structure and function of the cell membrane and its components and how each relates to the molecular structure of the body’s complex mixture of chemicals. No additional sources are listed.
Filename: PPdrugTr.rtf

Molecular Modeling: Conformation Analysis and Energy Minimization
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A 6 page paper discussing these two aspects of computational chemistry. The next generation of narrowly-targeted drugs seems to be about to appear over the horizon. Conformation analysis and molecular modeling play increasing roles in new drug research. Conformation is important in that it can change according to its environment; energy levels affect action. Drug developers need to discover the most effective conformation, but they also need to be able to retain that conformation despite conditions external to the molecule. Bibliography lists 7 sources. Includes a Newman projection diagram.
Filename: KSmolecModel.rtf


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